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Sildenafil
Generic Tablets or Compounded Sublingual Troches

FDA-approved generic sildenafil tablets ($29/month physician care; tablets paid to the pharmacy), or a compounded sublingual troche ($29/month care fee + compounded medication add-on) as an alternative dosage form — not FDA-approved, and onset data for compounded troches are limited. Troches are prepared by a licensed 503A compounding pharmacy (for example Hallandale Pharmacy or Valiant Compounding Pharmacy); the dispensing pharmacy is named on your prescription label. Prescribed by board-certified physicians after a free async consult.

Check Eligibility →How It Works
Drug Class
PDE5 inhibitor
Onset (tablet)
About 30–60 minutes
Duration
4–6 hours
Typical doses
25, 50, 100 mg

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Physician-verified manufacturer savings programs, copay cards and cash-price checks. Free, no sign-up. Program terms are set by the manufacturer or pharmacy.

Sildenafil savings

Tablet or sublingual troche?

Generic sildenafil tablets are FDA-approved and have the strongest evidence base; they usually take effect in about 30–60 minutes, and a high-fat meal can delay them. A sublingual troche dissolves under the tongue and is an alternative dosage form for patients who prefer not to swallow a tablet. Troches are compounded preparations, not FDA-approved; onset data for compounded troches are limited, and there are no head-to-head studies showing a troche works faster than a tablet. Troches are prepared by a licensed 503A compounding pharmacy (for example Hallandale Pharmacy or Valiant Compounding Pharmacy); the dispensing pharmacy is named on your prescription label. Your physician will help you choose.

How sildenafil works

Sildenafil blocks phosphodiesterase type 5 (PDE5), which normally breaks down cyclic GMP (cGMP) — the signaling molecule that relaxes smooth muscle and dilates blood vessels in the penile corpus cavernosum. By blocking PDE5, sildenafil allows cGMP to accumulate in response to sexual stimulation, producing and sustaining erection. Sexual arousal is still required; sildenafil enhances the body's natural response rather than creating one artificially.

Dosing

Take as directed by your physician (tablets are usually taken about 30–60 minutes before anticipated activity). Do not exceed one dose per 24 hours.

Side effects and contraindications

Common, typically mild: headache, facial flushing, nasal congestion, indigestion, visual color changes (rare blue tint).

Seek emergency care for erection lasting more than 4 hours (priapism), sudden vision loss, sudden hearing loss, or chest pain.

Do NOT take sildenafil if you: take nitrate medications (nitroglycerin, isosorbide) or use “poppers” — the combination can cause life-threatening hypotension; take riociguat; have had a recent heart attack or stroke; have severe cardiovascular disease. Use caution with alpha-blockers. Make sure your heart is healthy enough for sexual activity. If you have sudden vision or hearing loss, stop the medication and seek urgent care.

How it works at YourMD

  1. Free 5-minute eligibility screening. Online intake, no charge, no commitment.
  2. Free async consult — a board-certified internal medicine physician reviews your screening; no appointment needed. If a phone or video visit is needed, your physician will contact you.
  3. Personalized prescription sent to a pharmacy that works for you: a local retail pharmacy such as Walmart, or a low-cost online pharmacy; you pay the pharmacy directly. Troches are prepared by a licensed 503A compounding pharmacy (for example Hallandale Pharmacy or Valiant Compounding Pharmacy); the dispensing pharmacy is named on your prescription label. Compounded medication add-on: once your physician selects the compounding pharmacy, you receive a final price proposal (medication, shipping and our care fee) to accept before anything is made. You make one payment to YourMD for that proposal; the licensed compounding pharmacy prepares and ships it. Compounded medications are not FDA-approved.
  4. Ongoing care with unlimited asynchronous messaging.

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Medical disclaimer: Educational content, not medical advice. Page medically reviewed by Teja V. Surapaneni, MD, MS — Board-Certified Internal Medicine (NV, WA, OR, WI). Last reviewed: April 17, 2026