Medication use

Tirzepatide and Birth-Control Pills: Plan Before Dose Changes

If you use an oral hormonal contraceptive and take tirzepatide, make a contraception plan before starting or increasing the dose. This is a medication-specific issue; do not assume the same instructions apply to every weight-management drug or contraceptive method.

What to do next

  1. The Zepbound label advises switching to a non-oral contraceptive or adding a barrier method for four weeks after starting and four weeks after each dose increase.
  2. Ask your prescriber which option fits your current contraception and health history.
  3. Record the start and end dates for additional protection and review them with each dose escalation.
  4. Discuss pregnancy plans before treatment and contact the prescriber promptly if pregnancy occurs.

When to contact your care team

Zepbound should be discontinued when pregnancy is recognized; contact your prescriber for the next steps. If protection may have failed, seek prompt advice about emergency contraception rather than waiting for a routine visit. This guide does not replace the complete drug safety information.

Put it into practice

A useful question is: “My dose is increasing next week. What protection should I use, and through which date?” Keep the plan with your medication schedule so a later increase does not pass unnoticed. Tell the clinician if pills were missed or vomiting affected their use.

Notes for your next visit

Write these in your own notes or on a printed copy. Bring them to your follow-up.

  • My current contraceptive method:
  • Tirzepatide start or dose-increase date:
  • Agreed additional method and end date:

Sources and further reading

General education for adults. Follow your clinician’s individual plan and the current instructions for your prescribed product. This handout is not a complete medication guide. If instructions conflict, ask your clinician or pharmacist to clarify. For a medical emergency, call 911.